A Case of Potential Inborn Error of Metabolism as a Cause of Young Onset Psychosis

Introduction: Young onset psychosis has poor prognosis, and inborn errors of metabolism (IEM) can be easily missed. There is scarce information regarding IEM young in Malaysia. Case Report: A 15-year-old Malay girl presented at the age 8 years with a history intellectual disability neuro-regression, subsequently developing psychotic obsessive-compulsive symptoms several later. Organic workup revealed elevated lactate levels. Urine organic acid chromatogram moderate peak however most other investigations were normal. As MRI brain normal there are no neurological signs it appears less likely an underlying IEM-related aetiology for psychosis. Discussion: Various IEMs related to incidence very low quality evidence poor. Thus, any psychiatric presentation, particularly suggestive clinical signs, should warrant (including IEM) since these causes potentially reversible supplementation.